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pentobarbital will reduce the extent or impact of abiraterone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.Monitor Intently (1)pentobarbital will decrease the level or result of tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Loss of, or lessened reaction to tofaciti